Abstract: Based on the 110 level and above city panel data of 2000-2014 along the Yangtze River economic belt, DID (dual difference) method of empirical test of the effect of high speed railway construction of regional innovation space structure was used. The result shows that the railway construction significantly shortened the distance between the city highspeed rail along the Yangtze River economic zone and promoted the growth of innovation. High speed railway affects the innovation output of the cities in midwest, and is conducive to the formation of the east and west innovation interaction pattern, but also widens the gap between the cities with high railway and those without high speed railway. The unbalanced development trend of the spatial pattern of regional innovation is obvious. According to the analysis of the conclusion, some policy suggestions are put forward.

Key words: highspeed rail network, regional innovation, space structure, the Yangtze River economic belt, evolution

摘要： 基于长江经济带110个地级及以上城市2000—2014年面板数据，运用双重差分方法实证检验高铁建设对区域创新空间结构的影响。结果发现：高铁建设显著缩短了长江经济带高铁沿线各城市间的时空距离，促进其创新增长；高铁开通对中西部城市创新产出的溢出效应明显，有利于形成东中西创新联动格局，同时拉大了高铁和非高铁城市之间的创新差距，区域创新空间格局的非均衡发展趋势较为明显。根据结论，提出政策建议。

关键词: 高铁联网, 区域创新, 空间结构, 长江经济带, 演化